Molecular Basis Of Inheritance — DPP 4

20 NEET questions from Molecular Basis Of Inheritance, with answers and explanations. Attempt it as a timed test to get scoring, accuracy breakdown and mistake tracking.

Attempt this test free 20 questions · 30 minutes · +80 marks
1
Heterochromatin is
(a) Darkly stained region
(b) Loosely packed chromatin
(c) Transcriptionally inactive
  1. A Only (a)
  2. B Only (a) and (b)
  3. C Only (b) and (c)
  4. D Only (a) and (c)
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Correct answer: D

Heterochromatin is tightly packed region of DNA which is transcriptionally inactive. As it is tightly packed it gets darker stain.
2
For every single amino acid incorporated in peptide chain _______ ATP and _______ GTP molecules are used.
  1. A 1, 4
  2. B 1,6
  3. C 1,2
  4. D 1, 3
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Correct answer: C

1ATP → Activation of tRNA
2GTP → One in Peptide bond formation and other in ribosome movement to each new codon in the m-RNA.
3
In tailing, adenylate residues are added at 3' end
  1. A With the help of gyanyl transferase
  2. B In a template independent manner
  3. C With the help of methyl transferase
  4. D Of hn-RNA of E.coli
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Correct answer: B

Poly a tail formed at 3' end to stabilize RNA.
4
The structures which appear as "beads on string" in chromatin under electron microscope have all of the following histone proteins, except
  1. A $\mathrm { H } _ { 2 } \mathrm {~A}$
  2. B $\mathrm { H } _ { 3 }$
  3. C $\mathrm { H } _ { 2 } \mathrm {~B}$
  4. D $\mathrm { H } _ { 1 }$
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Correct answer: D

Nucleosomes have histone octamer, i.e., organised form of $\mathrm { H } _ { 2 } \mathrm {~A} , \mathrm { H } _ { 2 } \mathrm {~B} , \mathrm { H } _ { 3 }$ and $\mathrm { H } _ { 4 }$ histones. $\mathrm { H } _ { 1 }$ histone is not a part of histone octamer.
5
How many amino acids will be coded by the mRNA sequence $- 5 ^ { \prime }$ CCCUCAUAGUCAUAC3' if an adenosine residue is inserted after $12 ^ { \text {th } }$ nucleotide?
  1. A Five amino acids
  2. B Six amino acids
  3. C Two amino acids
  4. D Three amino acids
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Correct answer: C

Molecular Basis Of Inheritance – NEET-10226 So only two A.A will be formed.
6
If the sequence of one strand of DNA is 5'ATG C A T C G $3 ^ { \prime }$, find the sequence of complementary strand in $5 ^ { \prime } \rightarrow 3 ^ { \prime }$ direction
  1. A T AC G T A G C
  2. B C G A T G C A T
  3. C A T G C A T C G
  4. D A T C G T A C G
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Correct answer: B

Molecular Basis Of Inheritance – NEET-10178
7
Which of the following does not code for any proteins?
  1. A Micro-satellites
  2. B Exons
  3. C Mini-satellites
  4. D Both (1) and (3)
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Correct answer: D

(1) and (3)
8
In an mRNA, UTRs are present
  1. A At $5^{\prime}$ end only
  2. B Before stop codon only
  3. C After start codon only
  4. D Both, before start codon and after stop codon
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Correct answer: D

UTRs (Untranslated regions) are found at both 5'-end (before start codon) and at 3'end (after stop codon)
9
In-vitro template independent RNA synthesis is a feature of
  1. A RNA polymerase
  2. B Reverse transcriptase
  3. C Ochoa enzyme
  4. D DNA polymerase
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Correct answer: C

Ochoa enzyme → Polynucleotide phosphorylase.
10
Which of the following is not required during post transcriptional processing in eukaryotes?
  1. A Methyl guanosine triphosphate
  2. B Ligase
  3. C ScRNA
  4. D SnRNA
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Correct answer: C

Small cytoplasmic RNA → ScRNA
11
Prokaryotic transcription mechanism requires involvement of only one polymerase type and
(a) It occurs in cytoplasm only
(b) It is often coupled with translation
(c) It does not require splicing but capping is essential
  1. A All are correct
  2. B Both (b) & (c) are incorrect
  3. C Both (a) & (c) are incorrect
  4. D Only (c) is correct
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Correct answer: D

There is no capping and tailing in prokaryotes.
12
How many types of DNA polymerases are present in bacteria?
  1. A Five
  2. B Three
  3. C Two
  4. D One
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Correct answer: B

DNA Poll I

Pol II

Pol III
13
If there are 81 million bases in RNA of human cell, then calculate the total number of introns present in cDNA
  1. A 27 millions
  2. B Zero
  3. C Equal to ribonucleotides
  4. D Half the number of ribonucleotides
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Correct answer: B

Human RNA is processed RNA. So no intron in cDNA.
14
NHC structural proteins are
  1. A Basic proteins rich in lysine, arginine
  2. B Regulatory proteins
  3. C Catalytic proteins rich in tryptophan and arginine
  4. D Required for packaging of chromatin at higher levels
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Correct answer: D

15
Mark the incorrect option w.r.t. lac operon
  1. A Is under positive as well as negative control
  2. B Controls catabolic pathway
  3. C Shows feed back repression
  4. D Discovered by Jacob and Monod
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Correct answer: C

16
Read the following statements:
A. Variation at genetic level arises due to mutations.
B. Technique of DNA fingerprinting was initially developed by Alec Jeffreys
  1. A Only (B) is correct
  2. B Both (A) and (B) are correct
  3. C Only (A) is correct
  4. D Both (A) and (B) are correct
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Correct answer: B

17
The genes in eukaryotes are said to be split as
  1. A They have introns only
  2. B They have interrupted coding sequences
  3. C Mature m RNA contains both exons and introns
  4. D They have exons only
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Correct answer: B

The intervening sequences in between coding regions are called introns. Exons are coding regions of genes. Therefore, eukaryotic genes are split genes. In eukaryotes both introns and exons are present. $h n \mathrm { RNA }$ is processed in the nucleus and after processing it is called $m$ RNA that contains exons only.
18
Which of the following features is correct for bacteria?
  1. A Presence of intervening sequences in DNA
  2. B DNA does not show coiling
  3. C Linear ss-DNA representing single chromosome
  4. D DNA can be chromosomal as well as extrachromosomal
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Correct answer: D

Nuclear DNA → Nucleoid
Extrachromosomal → Plasmid
19
The technique of DNA fingerprinting was developed by
  1. A Lalji Singh
  2. B V.K. Kashyap
  3. C Alec Jeffreys
  4. D Kim and Klug
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Correct answer: C

20
In t-RNA
  1. A CCA - OH is present at 5 -end
  2. B TΨC loop for attaching the amino acid
  3. C DHU loop for binding with AA - activating enzyme
  4. D There are three recognition sites
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Correct answer: C

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