Molecular Basis Of Inheritance — DPP 7

20 NEET questions from Molecular Basis Of Inheritance, with answers and explanations. Attempt it as a timed test to get scoring, accuracy breakdown and mistake tracking.

Attempt this test free 20 questions · 30 minutes · +80 marks
1
The first codon discovered by Nirenberg and Mathaei was
  1. A GGG
  2. B CCC
  3. C UUU
  4. D AAA
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Correct answer: C

2
What is correct for bacterial transcription?
  1. A mRNA requires processing to become active
  2. B Translation can begin when mRNA is fully transcribed
  3. C Transcription and translation takes place in the same compartment
  4. D Rho factor initiates the process
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Correct answer: C

Transcription and translation take place in cytoplasm.
3
Histone proteins are rich in
  1. A Tryptophan, Lysine
  2. B Arginine, Lysine
  3. C Histidine, Arginine
  4. D Histidine, Tryptophan
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Correct answer: B

4
A DNA strand on which new strand is produced is called
  1. A complementary
  2. B template
  3. C primer
  4. D elongating
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Correct answer: B

5
Pribnow box is a consensus of _______ bases, forming a binding site for E. coli RNA polymerase at promotor
  1. A TATAAT
  2. B AGGAGG
  3. C CAAT
  4. D GC
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Correct answer: A

6
Splicing is one of the steps of post-transcriptional modifications which occurs in
  1. A Nucleus
  2. B Cytoplasm
  3. C ER
  4. D Ribosomes
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Correct answer: A

7
The protein which helps to unwind DNA double helix during replication is
  1. A DNA polymerase
  2. B DNA gyrase
  3. C helicase
  4. D DNA topoisomerase
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Correct answer: C

8
The length of DNA molecule greatly exceeds the dimensions of the nucleus in the eukaryotic cells. How is this DNA accomodated?
  1. A Super coiling in nucleosomes
  2. B DNase digestion
  3. C Through elimination of repetitive DNA
  4. D Deletion of non-essential genes
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Correct answer: A

9
Why does cytosine make pair with guanine and not with adenine?
  1. A Polar nature of C and A
  2. B C - A pair would not reach across the double helix
  3. C C - A pair would be wider than double helix
  4. D Hydrogen bond forming functional groups are not complementary between C and A
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Correct answer: D

10
Which is incorrect regarding nucleosome?
(a) A typical nucleosome contain 200 bp of DNA helix
(b) Histone are rich in the basic amino acid residue lysines & arginines
(c) The packaging of chromatin at higher level require additional set of proteins that collectively are referred to as Non-histone chromosomal (NHC) protein
  1. A a only
  2. B a & c both
  3. C c only
  4. D None
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Correct answer: D

11
Identification and binding of RNA polymerase to the promoter sequence is a function of
  1. A Rho factor
  2. B Sigma factor
  3. C Beta factor
  4. D Omega factor
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Correct answer: B

12
A nucleoside is
  1. A purine / pyrimidine + phosphate
  2. B purine / pyrimidine + sugar
  3. C pyrimidine + purine + phosphate
  4. D Purine + sugar + phosphate
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Correct answer: B

13
In DNA replication, primer strand is formed by
  1. A A small piece of deoxyribonucleotide polymer
  2. B A small piece of ribonucleotide polymer
  3. C Deoxyribonucleotides + pyrophosphates
  4. D DNA replicase + nucleotide + ATP
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Correct answer: B

14
Which of the following is Pribnow box?
  1. A 5' AATAAT3'
  2. B 5' ATATTA3'
  3. C 5' TATAAT3'
  4. D 5TAATTA3'
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Correct answer: C

15
DNA polymerase enzyme was discovered by
  1. A Kornberg
  2. B Nirenberg
  3. C Khorana
  4. D Ochoa
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Correct answer: A

16
In which of the following, double stranded RNA is present?
  1. A bacteria
  2. B $\phi \times 174$
  3. C retrovirus
  4. D reovirus
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Correct answer: D

17
Termination of polypeptide synthesis in bacteria differs from eukaryotes in
  1. A Having different termination codons
  2. B Being GTP dependent
  3. C Involving more than one type of release factors
  4. D All of these
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Correct answer: C

18
In protein synthesis, which of the following are required for the synthesis of charged tRNA?
  1. A Amino acid, GTP, initiation codon, ribosome
  2. B Amino acid, ATP, $\mathrm { Mg } ^ { + + }$, enzyme, tRNA
  3. C Amino acid, ATP, K+, enzyme, mRNA
  4. D Aminoacyl tRNA, ribosome, initiation codon, release factor
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Correct answer: B

19
Select the mis-matched pair.
  1. A $\phi \times 174$ bacteriophage - 5386 bases
  2. B λ phage - ds RNA
  3. C E.coli - ds DNA
  4. D Human genome $\quad-3.3 \times 10^{9} \mathrm{bp}$
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Correct answer: B

λ phage : dsDNA
20
Which of the following serves as a termination codon?
  1. A AUG
  2. B CGC
  3. C UAG
  4. D GUG
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Correct answer: C

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