Molecular Basis Of Inheritance — DPP 6

20 NEET questions from Molecular Basis Of Inheritance, with answers and explanations. Attempt it as a timed test to get scoring, accuracy breakdown and mistake tracking.

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1
The DNA strand showing replication using Okazaki fragments also shows
  1. A Continuous growth in $5 ^ { \prime } \rightarrow 3 ^ { \prime }$ direction
  2. B Discontinuous growth on $5 ^ { \prime } \rightarrow 3 ^ { \prime }$ parental strand
  3. C Discontinuous growth on $3 ^ { \prime } \rightarrow 5 ^ { \prime }$ parental strand
  4. D Involvement of one primer only
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Correct answer: B

2
Regarding to features of double helix structure of DNA which of the following is wrong
  1. A Two polynucleotide chains have antiparallel polarity
  2. B The bases in two strands are paired through phosphodiester bonds
  3. C Adenine form two hydrogen bonds with thymine
  4. D The pitch of the helix is 3.4 nm
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Correct answer: B

3
VNTRs are
a. Small DNA sequences arranged tandemly in many copy number.
b. Surrounded by conserved restriction sites.
c. Microsatellites
d. Present in the same copy number in different chromosomes of an individual.
  1. A a and b
  2. B b and c
  3. C c and d
  4. D a and d
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Correct answer: A

VNTRs - Minisatelites
4
Untranslated regions are
  1. A Present at 5' end of mRNA after start codon
  2. B Not required for efficient translation process
  3. C Present at $3^{\prime}$ end before stop codon
  4. D Present at both $5^{\prime}$ and $3^{\prime}$ end of mRNA.
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Correct answer: D

UTRs present on mRNA are required for efficient translation process.
5
Gene battery model was proposed by
  1. A Jacob and Monad
  2. B Gamow
  3. C H.G. Khorana
  4. D Britten and Davidson
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Correct answer: D

6
DNA was first discovered by
  1. A Beadle and Tatum
  2. B Watson and Crick
  3. C Friedrich Miescher
  4. D A. Kornberg
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Correct answer: C

7
RNA primer is removed by
  1. A DNAP-I
  2. B DNAP-II
  3. C DNAP-III
  4. D Primase
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Correct answer: A

DNA polymerase I has exonuclease activity.
8
Non-histone proteins
  1. A Are of five types
  2. B Are involved in nucleosome formation
  3. C Control gene expression
  4. D Are basic proteins
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Correct answer: C

9
Select the true statement(s) for AUG.
A. It codes for an amino acid methionine
B. It is an initiation codon
C. It is a non-degenerate codon
  1. A Only A
  2. B Only A and B
  3. C Only B and C
  4. D All A, B and C
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Correct answer: D

AUG codes for an amino acid methionine and it also acts as initiation codon. As methionine is coded by AUG only, it is non-degenerate codon.
10
Which RNA occurs abundantly in a cell?
  1. A r RNA
  2. B t RNA
  3. C m RNA
  4. D Primer RNA
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Correct answer: A

11
Which of the following is/are wrong regarding double helical structure of DNA
(a) DNA is made up of two polynucleotide chains
(b) Backbone of DNA is constituted by sugar & Nitrogenous base
(c) The two chain have anti parallel polarity
(d) The pitch of the helix is $3.4 \mathrm {~A} ^ { \circ }$
  1. A b & c
  2. B a & d
  3. C b only
  4. D b & d
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Correct answer: D

12
In a given sample of nucleic acid $\mathrm { G } + \mathrm { A }$ content is not equal to $\mathrm { C } + \mathrm { T }$. This indicates that sample is
  1. A GC rich
  2. B AT rich
  3. C single-stranded DNA
  4. D double-stranded DNA
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Correct answer: C

13
Which one of the following DNA molecules will melt at the lowest temperature?
  1. A $5{ }^{\prime}$ TGCAGCGGCAGCG3,' 3'ACGTCGCCGTCGC5'
  2. B 5'CCCGGACCGATGC3', 3'GGGCCTGGCTACG5'
  3. C 5'AATTAAACGCAATA3', 3'TTAATTTGCGTTAT5'
  4. D $5{ }^{\prime}$ GGCCATCCGTGCC3', 3́CCGGTAGGCACGG5́
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Correct answer: C

14
In eukaryotes, the RNA polymerase that synthesises tRNA is RNA polymerase ______ and is also responsible for formation of ________ rRNA.
  1. A II, 5.8 S
  2. B I, 5 S
  3. C III, 5 S
  4. D II, 18 S
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Correct answer: C

15
Which of the following is not a criteria for determination of genetic material
  1. A Ability of replication
  2. B Chemically and structurally stable
  3. C It should be non mutable
  4. D Ability to expres itself in form of Mendelian characters
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Correct answer: C

16
To prove that DNA is the genetic material, Griffith used
  1. A Neurospora crassa
  2. B Drosophila melanogaster
  3. C Diplococcus pneumoniae
  4. D Escherichia coli
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Correct answer: C

17
In prokaryotes, DNA gyrase has _______ activity.
  1. A Exonuclease
  2. B Topoisomerase
  3. C Ligase
  4. D Polymerase
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Correct answer: B

18
Select the correct one (w.r.t. Wobble hypothesis)
  1. A Third base of a codon lacks vibrating capacity
  2. B Third base can establish H-bonds even with the non complementary anticodon
  3. C Specificity of a anticodon is particularly determined by first two codon
  4. D Major cause of degeneracy is the first two N -bases of codon
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Correct answer: B

GUG → 3rd position can establish H - bond even with the non-complementary anticodon.
19
With respect to the bacteriophage, choose the correct sequence of Harshey-Chase experiment.
  1. A (a) Blending, (b) Infection, (c) Centrifugation
  2. B (a) Infection, (b) Centrifugation, (c) Blending
  3. C (a) Infection, (b) Blending, (c) Centrifugation
  4. D (a) Centrifugation, (b) Blending, (c) Infection
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Correct answer: C

20
The two stands of DNA are
  1. A Similar in nature and complementary
  2. B Antiparallel and complementary
  3. C Always single stranded
  4. D Rarely double stranded
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Correct answer: B

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