Molecular Basis Of Inheritance — DPP 5

20 NEET questions from Molecular Basis Of Inheritance, with answers and explanations. Attempt it as a timed test to get scoring, accuracy breakdown and mistake tracking.

Attempt this test free 20 questions · 30 minutes · +80 marks
1
Tryptophan operon is
  1. A Catabolic system
  2. B Repressible system
  3. C Inducible system
  4. D Having three structural genes
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Correct answer: B

2
A nucleosome is composed of
  1. A Positively charged DNA and negatively charged histone octamer
  2. B A negatively charged $\mathrm { H } _ { 1 }$ histone and positively charged DNA molecule
  3. C Negatively charged DNA and positively charged histone octamer
  4. D Negatively charged lysines and positively charged arginine amino acids
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Correct answer: C

The negatively charged DNA is wrapped around the positively charged histone octamer to form a structure called nucleosome.
3
Repetitive sequences are stretches of DNA with repeated bases many times in a genome, but
(a) These sequences are of no transcriptional function
(b) These are associated with euchromatin region
(c) These helps to identify a person on the basis of its DNA specificity
  1. A All are correct
  2. B Only (b) is incorrect
  3. C Both (a) & (b) are correct
  4. D Both (b) & (c) are incorrect
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Correct answer: B

4
In which step of DNA profiling, nitrocellulose membrane is used?
  1. A Denaturation
  2. B Autoradiography
  3. C Blotting
  4. D DNA amplification
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Correct answer: C

Southern Blotting
5
The longest RNA in an eukaryotic cell is
  1. A rRNA
  2. B mRNA
  3. C tRNA
  4. D ScRNA
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Correct answer: B

6
Which of the following bonds is not present in DNA?
  1. A $\beta - 1 ^ { \prime } - 9 - \mathrm { N } -$ glycosidic bond
  2. B $3 ^ { \prime } - 5 ^ { \prime }$ phosphodiester bond
  3. C $\beta - 1 ^ { \prime } - 1 - \mathrm { N } -$ glycosidic bond
  4. D $\beta - 1 ^ { \prime } - 2 - \mathrm { N } -$ glycosidic bond
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Correct answer: D

$\beta-1^{\prime}-9^{\prime} \rightarrow$ Glycosidic bond → Sugar and Purines
$\beta-1^{\prime}-1^{\prime} \rightarrow$ Glycosidic bond → Sugar and Pyrimidine
$3^{\prime}-5^{\prime} \rightarrow$ Phosphodiester bond → Sugar and Phosphate
7
The accessibility of promoter regions of bacterial DNA in many cases regulated by the interaction of proteins with sequences termed
  1. A Regulators
  2. B Structural genes
  3. C Inhibitor genes
  4. D Operators
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Correct answer: D

If repressor is attached at operator their is no synthesis of mRNA.
8
The experimental proof for semiconservative mode of DNA replication was first shown in a bacterium, by
  1. A Meselson and Stahl
  2. B Hershey and Chase
  3. C Jacob and Monod
  4. D Alec Jeffreys
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Correct answer: A

Meselson and Stahl first time proved semi conservative mode of DNA replication in a bacterium, E. coli.
9
In tryptophan operon
  1. A Non-proteinaceous aporepressor is synthesised by R-gene
  2. B Normally chorismic acid is not converted into tryptophan
  3. C Repression is mostly connected with a catabolic pathway
  4. D Enzymes produced by structural genes normally present in the cell
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Correct answer: D

10
Adenine and guanine are
  1. A Heterocyclic
  2. B Have nitrogen only at position 1 and 3
  3. C 9-membered double ring structures
  4. D Both (1) & (3)
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Correct answer: D

A and $G$ have nitrogen at $1 ^ { \text {st } } , 3 ^ { \text {rd } } , 7 ^ { \text {th } }$ and $9 ^ { \text {th } }$ position.
11
Find the incorrect match
  1. A Central dogma : F. Crick
  2. B Reverse central : Temin and Baltimore dogma
  3. C Split genes : Kornberg
  4. D mRNA : Jacob and Monad
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Correct answer: C

Split gene was discovered by Richard J. Roberts and Phillip Sharp.
12
Mark the mismatched pair.
  1. A UGG - Non-degenerate codon
  2. B GUG - Non-ambiguous codon
  3. C UAG - Non-sense codon
  4. D AUG - Initiator codon
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Correct answer: B

GUG — Ambiguous codon.
13
For the strand separation and stabilisation during DNA replication which of the following sets of enzymes and proteins are required?
  1. A SSBP, gyrase, primase
  2. B Topoisomerase, helicase, ligase
  3. C Gyrase, ligase, primase
  4. D Topoisomerase, helicase, SSBP
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Correct answer: D

Topoisomerase - Remove twisting stress
Helicase - Unwind DNA
SSBP - Single strand binding protein
14
Splicing is necessary for preparing a mature transcript and its movement to cytoplasm. It requires
  1. A scRNA and proteins
  2. B snRNA and proteins
  3. C scRNA and snRNA
  4. D scRNA only
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Correct answer: B

15
Recognition sequence for transcription in prokaryotes is
  1. A TATATAT
  2. B TATAAT
  3. C TATAAAT
  4. D CAAT
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Correct answer: B

16
Select the incorrect match(es) from the following
Molecular Basis Of Inheritance – NEET-10034
  1. A a, b and c
  2. B a and d
  3. C d only
  4. D b and c only
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Correct answer: B

Minisatellites are VNTRs. VNTRs show very high degree of polymorphism. The size of VNTR varies from 0.1 to 20 kb.
17
Synthesis of leading and lagging strand require
  1. A Single primer
  2. B Single and many primers respectively
  3. C Many and single primers respectively
  4. D Many primers
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Correct answer: B

Leading → Continuous strand have polarity $3 ^ { \prime } \rightarrow 5 ^ { \prime }$ end it needs single primer
Lagging → Discontinuous strand have polarity $5 ^ { \prime } \rightarrow 3 ^ { \prime }$ end it needs multiple primer
18
Which of the following DNA forms has maximum number of base pairs per turn?
  1. A A-DNA
  2. B B-DNA
  3. C C-DNA
  4. D Z-DNA
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Correct answer: D

19
When the genomes of two people are cut using the same restriction enzyme, the length and number of fragments obtained are different, this is called
  1. A PCR
  2. B RFLP
  3. C EST
  4. D Northern blotting
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Correct answer: B

RFLP → Restriction Fragment Length polymorphism.
20
Satellite DNA
  1. A Codes for proteins which are needed in the chloroplast
  2. B Codes enzymes for Krebs' cycle
  3. C Does not code for proteins
  4. D Form a little portion of human genome
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Correct answer: C

Bulk DNA of human genome is satellite DNA. Less than 2% of human genome codes for proteins. Satellite DNA which is major portion of human DNA normally does not code for any protein.

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